Raynaud phenomenon: from GWAS to drug repurposing

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Abstract

The identification of novel risk variants in the largest genome-wide association study of Raynaud phenomenon to date provides insights into the pathophysiology of the condition, including the potential role for α2A-adrenoceptors, and suggests opportunities for drug repurposing.

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Herrick, A. L., & Orozco, G. (2024). Raynaud phenomenon: from GWAS to drug repurposing. Nature Reviews Rheumatology, 20(3), 139–140. https://doi.org/10.1038/s41584-024-01076-x

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