Asymmetric hydrogenation of disubstituted furans

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Abstract

An enantioselective hydrogenation of disubstituted furans has been developed by using a chiral ruthenium catalyst with N-heterocyclic carbene ligands. This reaction converts furans into valuable enantioenriched disubstituted tetrahydrofurans. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Wysocki, J., Ortega, N., & Glorius, F. (2014). Asymmetric hydrogenation of disubstituted furans. Angewandte Chemie - International Edition, 53(33), 8751–8755. https://doi.org/10.1002/anie.201310985

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