The association between posterior brain cerebral circulation calcification and coronary arteries calcification and its stroke risk in a Saudi population: a retrospective study

Abstract

Background: Anterior cerebral circulation calcification and stroke occurrence association is well established in the literature. Posterior cerebral circulation calcification associated with coronary calcification and stroke incidence has not been properly investigated in Saudi Arabia. Therefore, the present study aimed to investigate the clinical relationship between posterior cerebral circulation calcification and coronary artery calcifications and to describe the association between risk factors and stroke occurrence based on computed tomography imaging. Results: A total of 101 patients were enrolled in the study. The mean age was 64.9 ± 12.4. Of the patients, 69.3 were male. Most of the patients were Saudi (72.3%), 28.6% were smokers, 36.4% were overweight, and 22.1% were obese. Exactly 61.4% had mild coronary artery calcification, 26.7% had moderate calcification, and 11.9% had severe calcification. 34.7% had an anterior stroke, and 23.8% had a posterior stroke. Posterior cerebral circulation calcification was more evident in patients with coronary artery calcification, and it increased with the severity level (p = 0.001). Posterior cerebral circulation calcification was significantly associated with stroke (67.4%, p = < 0.001). Conclusion: Coronary artery calcification is significantly associated with posterior cerebral circulation calcification. Furthermore, stroke incidence increased with the presence of posterior cerebral circulation calcification.