Ozone Therapy in Medicine and Dentistr

Abstract

The aim of this review is to provide an overview of the status of the use of ozone therapy in medicine and dentistry, based on a search for scientific articles and clinical studies. A search in the PubMed search engine revealed a positive trend, namely a significant increase in clinical research in the period from 2015. to date, especially in the last three years, indicating an increasing interest in clinical application. The development of safe devices and application methods contributes to this. Ozone was discovered over a hundred years ago and has since been used in many areas, including medicine. Numerous studies have demonstrated the positive effect of ozone on antioxidant capacity and on modulations in the vascular, haematological and immunological systems, as well as its effectiveness as an adjunct to conventional therapies. The strong oxidising effect of ozone enables the suppression of almost all microorganisms, which is why ozone exhibits bactericidal, virucidal and fungicidal properties. However, despite the positive effects that enable its broad application in medicine, the use of ozone in dentistry has not shown the expected effectiveness. The local application of ozone as an antimicrobial agent for the non-surgical treatment of periodontal diseases is a good tool to support periodontal therapy.