Reactogenicity and immunogenicity of a Lyme disease vaccine in children 2-5 years old

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Abstract

Two doses of a recombinant Lyme disease vaccine (15 and 30 microg) were administered to children 2-5 years old (0-1-month schedule) and were well tolerated. Both doses were highly immunogenic with geometric mean titers 1 month after vaccination of 4366 and 9877 ELISA units (EU)/mL, respectively. Nearly all subjects had antibody levels of > or = 1400 EU/mL, suggesting protective tick titre for one tick season. © 2000 Infectious Diseases Society of America.

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Beran, J., De Clercq, N., Dieussaert, I., & Van Hoecke, C. (2000). Reactogenicity and immunogenicity of a Lyme disease vaccine in children 2-5 years old. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America, 31(6), 1504–1507. https://doi.org/10.1086/317479

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