Intramucosal adenocarcinoma of the ileum originated 40 years after ileosigmoidostomy

1Citations
Citations of this article
6Readers
Mendeley users who have this article in their library.

Abstract

Background: Small bowel adenocarcinomas (SBAs) are rare carcinomas. They are asymptomatic and usually neither endoscopy nor contrast studies are performed for screening. Case presentation: A 72-year-old Japanese male had a positive fecal occult blood test at a regular check-up in 2006. He suffered appendicitis and received an ileosigmoidostomy in 1966. A colonoscopy revealed an irregular mucosal lesion with an unclear margin at the ileum side of the anastomosis. A mucosal biopsy specimen showed adenocarcinoma histopathologically. Excision of the anastomosis was performed for this patient. The resected specimen showed a flat mucosal lesion with a slight depression at the ileum adjacent to the anastomosis. Histological examination revealed a well differentiated intramucosal adenocarcinoma (adenocarcinoma in situ). Immunohistological staining demonstrated the overexpression of p53 protein in the adenocarcinoma. Conclusion: Adenocarcinoma of the ileum at such an early stage is a very rare event. In this case, there is a possibility that the ileosigmoidostomy resulted in a back flow of colonic stool to the ileum that caused the carcinogenesis of the small intestine. © 2009 Sameshima et al; licensee BioMed Central Ltd.

Cite

CITATION STYLE

APA

Sameshima, S., Tomozawa, S., Koketsu, S., Okada, T., Miyato, H., Iijima, M., … Kaji, T. (2009). Intramucosal adenocarcinoma of the ileum originated 40 years after ileosigmoidostomy. World Journal of Surgical Oncology, 7. https://doi.org/10.1186/1477-7819-7-41

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free