N-arylalkyl-N-phenylhydroxylamines as novel photo-induced DNA-cleaving agents

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Abstract

Single-strand cleavage of DNA was accomplished by photolysis of various N-arylalkyl-N-phenylhydroxylamines under aerobic conditions for 3 h with 312 nm UV light, which functioned as the trigger to initiate the new and controllable DNA cleavage process.

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Hwu, J. R., Tsay, S. C., Chen, B. L., Patel, H. V., & Chou, C. T. (1994). N-arylalkyl-N-phenylhydroxylamines as novel photo-induced DNA-cleaving agents. Journal of the Chemical Society, Chemical Communications, (12), 1427–1428. https://doi.org/10.1039/C39940001427

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