Abstract
Comprehending cellular changes of radiation-induced brain injury is crucial to prevent and treat the pathology. We provide a unique open dataset of proton-irradiated mouse brains consisting of medical imaging, radiation dose simulations, and large-scale microscopy images, all registered into a common coordinate system. This allows dose-dependent analyses on single-cell level.
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Soltwedel, J., Suckert, T., Beyreuther, E., Schneider, M., Boucsein, M., Bodenstein, E., … Dietrich, A. (2023). Slice2Volume: Fusion of multimodal medical imaging and light microscopy data of irradiation-injured brain tissue in 3D. Radiotherapy and Oncology, 182. https://doi.org/10.1016/j.radonc.2023.109591
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