A moving target: Inactivating btk mutations as drivers of follicular lymphoma

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Abstract

Drugs that target Bruton tyrosine kinase (BTK) have been highly successful and changed the landscape of therapies in B-cell lymphomas. However, their lower rates of effectiveness in follicular lymphoma are unexplained. Recent work describes inactivating BTK mutations that show that at least some follicular lymphomas do not require BTK.

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APA

Afaghani, J., & Taylor, J. (2021). A moving target: Inactivating btk mutations as drivers of follicular lymphoma. Clinical Cancer Research, 27(8), 2123–2125. https://doi.org/10.1158/1078-0432.CCR-21-0140

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