Decreased skin superoxide dismutase activity by a single exposure of ultraviolet radiation is reduced by liposomal superoxide dismutase pretreatment

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Abstract

The effect of a single exposure to UV radiation on skin superoxide dismutase (SOD) activity was examined in mice. A significant decrease in SOD activity was observed 24 and 48 h after UV irradiation, returning to the normal level by 72 h after irradiation. Decreased SOD activity after UV exposure was reduced by pretreatment with liposomal SOD (L-SOD). This protective effect of L-SOD may have potential clinical application for photodermatologic reactions. © 1987.

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Miyachi, Y., Imamura, S., & Niwa, Y. (1987). Decreased skin superoxide dismutase activity by a single exposure of ultraviolet radiation is reduced by liposomal superoxide dismutase pretreatment. Journal of Investigative Dermatology, 89(1), 111–112. https://doi.org/10.1111/1523-1747.ep12580453

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