IL-17A is a central regulator of lung tumor growth

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Abstract

In a recent study we reported increased expression of IL-17A in the lung of patients with lung adenocarcinoma. Local blockade of IL-17A in the lung, in a model of lung cancer revealed enhanced anti-tumor immunity characterized by increased IFNγ, a diminished T-regulatory cell number and reduced tumor growth. © 2012 Landes Bioscience.

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Reppert, S., Koch, S., & Finotto, S. (2012). IL-17A is a central regulator of lung tumor growth. OncoImmunology, 1(5), 783–785. https://doi.org/10.4161/onci.19735

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