Treatment of trichomoniasis in females with and without gonorrhoea

Abstract

46 women with trichomoniasis and gonorrhoea were treated with nimorazole (300 mg twice daily for 7 days) and a trichomonal cure rate of 90.2% was noted. In addition, 53 of 112 patients with trichomoniasis but without gonorrhoea were treated with metronidazole (200 mg three times a day for 7 days) and 59 with nimorazole (300 mg twice daily for 7 days) in a randomized trial. The cure rates were 96 and 90.5% respectively. There was no significant difference in the results noted in the two groups. Neither the trichomonal infection itself nor the result of antitrichomonal therapy was affected by antigonococcal therapy (one day treatment with ampicillin or single dose therapy with doxycycline). No increase was noted in the frequency of candidiasis after antitrichomonal therapy (in patients without gonorrhoea) or after antigonococcal therapy, but there was substantial variation between consecutive specimens in the prevalence of C. albicans.