Direct recordings of grid-like neuronal activity in human spatial navigation

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Abstract

Grid cells in the entorhinal cortex appear to represent spatial location via a triangular coordinate system. Such cells, which have been identified in rats, bats and monkeys, are believed to support a wide range of spatial behaviors. Recording neuronal activity from neurosurgical patients performing a virtual-navigation task, we identified cells exhibiting grid-like spiking patterns in the human brain, suggesting that humans and simpler animals rely on homologous spatial-coding schemes. © 2013 Nature America, Inc. All rights reserved.

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Jacobs, J., Weidemann, C. T., Miller, J. F., Solway, A., Burke, J. F., Wei, X. X., … Kahana, M. J. (2013). Direct recordings of grid-like neuronal activity in human spatial navigation. Nature Neuroscience, 16(9), 1188–1190. https://doi.org/10.1038/nn.3466

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