Copper-catalyzed borylative coupling of vinylazaarenes and N-Boc imines

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Abstract

Cu-catalyzed three-component couplings of vinylazaarenes, B2(pin)2, and N-Boc imines are described. Oxidation of the initially formed boronate gives azaarene-containing, Boc-protected amino alcohols with reasonable to good diastereoselectivities.

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Smith, J. J., Best, D., & Lam, H. W. (2016). Copper-catalyzed borylative coupling of vinylazaarenes and N-Boc imines. Chemical Communications, 52(19), 3770–3772. https://doi.org/10.1039/c6cc00603e

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