Increasing Clindamycin and Trimethoprim-Sulfamethoxazole Resistance in Pediatric Staphylococcus aureus Infections

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Abstract

The epidemiology of Staphylococcus aureus infection in children is dynamic. We conducted a retrospective observational study on pediatric clinical cultures, performed between 2005 and 2017, that grew S aureus to determine temporal trends in antibiotic resistance. Although methicillin resistance declined, clindamycin and trimethoprim-sulfamethoxazole resistance increased significantly, especially among community-onset isolates.

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Khamash, D. F., Voskertchian, A., Tamma, P. D., Akinboyo, I. C., Carroll, K. C., & Milstone, A. M. (2019). Increasing Clindamycin and Trimethoprim-Sulfamethoxazole Resistance in Pediatric Staphylococcus aureus Infections. Journal of the Pediatric Infectious Diseases Society, 8(4), 351–353. https://doi.org/10.1093/jpids/piy062

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