Rituximab therapy in autoimmune pulmonary alveolar proteinosis

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Abstract

Idiopathic pulmonary alveolar proteinosis is presumed to be an autoimmune disorder that may lead to pulmonary insufficiency. However, steroids do not appear to be effective and the standard of therapy is whole-lung lavage. We report the first case of successful therapy with rituximab, which addresses the pathogenic mechanism of pulmonary alveolar proteinosis. Copyright©ERS Journals Ltd 2009.

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Borie, R., Debray, M. P., Laine, C., Aubier, M., & Crestani, B. (2009). Rituximab therapy in autoimmune pulmonary alveolar proteinosis. European Respiratory Journal, 33(6), 1503–1506. https://doi.org/10.1183/09031936.00160908

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