Long-standing scirrhous breast carcinoma en cuirasse

Abstract

Background: The stromal reaction may be one of the key factors in the development of breast carcinomas. Case Report: We report the case of an 80-year-old female patient who ignored a very slow growing, extensive scirrhous breast carcinoma for almost 20 years duration. Results: Histopathology analysis revealed a Scarff Bloom Richardson (SBR)3-grade, estrogen receptor (ER)-positive (80%), progesterone receptor (PR)-positive (10%), HER2/neu-negative, lobular-invasive, scirrhous breast carcinoma with large cells. Conclusion: A strong peritumoral fibrous stromal reaction may explain the longstanding evolution of the tumor without any distant metastases. Copyright © 2010 S. Karger AG, Basel.