In vitro activities of ketolide HMR 3647, macrolides, and clindamycin against coryneform bacteria

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Abstract

The in vitro activity of ketolide HMR 3647 against coryneform bacteria isolated from clinical samples was evaluated. Except against Corynebacterium jeikeium and C. urealyticum, HMR 3647 showed high activity against Corynebacterium spp., being more active than 14- and 16-membered macrolides, azithromycin, or clindamycin. HMR 3647 also had high in vitro activity against Brevibacterium spp. and Listeria monocytogenes.

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Martínez-Martínez, L., Pascual, A., Suárez, A. I., & Perea, E. J. (1998). In vitro activities of ketolide HMR 3647, macrolides, and clindamycin against coryneform bacteria. Antimicrobial Agents and Chemotherapy, 42(12), 3290–3292. https://doi.org/10.1128/aac.42.12.3290

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