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Rational and semirational protein design

Humana Press Inc., (2018), 15-23
DOI: 10.1007/978-1-4939-7366-8_2
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Abstract

This mini review gives an overview over different design approaches and methodologies applied in rational and semirational enzyme engineering. The underlying principles for engineering novel activities, enantioselectivity, substrate specificity, stability, and pH optimum are summarized.

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Korendovych, I. V. (2018). Rational and semirational protein design. In Methods in Molecular Biology (Vol. 1685, pp. 15–23). Humana Press Inc. https://doi.org/10.1007/978-1-4939-7366-8_2

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