Inferring Protein-Protein Interactions (PPIs) Based on Computational Methods

Abstract

Proteins are involved in many essential cellular processes, such as metabolism and signalling. They function by interacting with other molecules within the cell. Thus, protein interaction is one of the important keys to understand protein functions. As a consequence of the development of high-throughput experimental methods for detecting protein interactions, large volumes of data are now available. Although the data are valuable, there are limitations to their application. Therefore, computational methods are helpful tools for predicting protein interactions. With the increase in genome sequence data, the importance of computational methods in this field is growing more and more.