Successful treatment of a desmoid tumor with doxorubicin

Abstract

Background. Desmoid tumors are the source of significant morbidity and mortality in patients with Gardner syndrome. Methods. The authors present a case report and review of the literature. Results. A young woman with an extensive abdominal desmoid had a prolonged response to doxorubicin after she did not respond to more conventional treatments. Conclusions. To the authors' knowledge, this is the first report of the successful treatment of desmoids with doxorubicin used as a single agent. Reports of the efficacy of chemotherapy in these and related tumors are reviewed. Copyright © 1993 American Cancer Society