Direct nitration of five membered heterocycles

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Abstract

Direct nitration of a variety of furans, pyrroles, thiophenes, pyrazoles, imidazoles, isoxazoles and thiazoles (17 compounds) with nitric acid/trifluoroacetic anhydride affords mononitro derivatives in average yield of 60 %. © ARKAT.

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Katritzky, A. R., Scriven, E. F. V., Majumder, S., Akhmedova, R. G., Akhmedov, N. G., & Vakulenko, A. V. (2005). Direct nitration of five membered heterocycles. Arkivoc, 2005(3), 179–191. https://doi.org/10.3998/ark.5550190.0006.320

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