Antibiotic resistance profile of Escherichia coli isolates from Colibacillosis in and around Pantnagar, India

Abstract

Aim: The present study was designed to study antibiotic resistance profile of E. coli isolates from colibacillosis in layers in and around Pantnagar. Materials and Methods: A total of 20 isolates of E. coli were recovered from 35 cases of colibacillosis in layers during necropsy. Antibiogram was studied via disc diffusion method against 12 antibiotics. Results: Results showed multiple drug resistance in 52.63% E. coli isolates. Serotyping of these isolates revealed 10 'O' group serotypes, predominantly O80 and O84 accounting for 31.57%. O80, O110, O119 and O132 have previously been isolated from human suggesting its zoonotic importance. A high degree of resistance was seen against cephalexin (73.68%) whereas chloramphenicol was found to be maximally (100%) effective. Emergence of enhanced mechanism of resistance to a variety of frequently used antibiotics is an increasing public health problem. Conclusion: It can be concluded that animals and human are at potential risk of acquiring infection with multi drug resistant strain of E. coli.