Ethyl 4,4"-difluoro-5'-hydroxy-1,1':3',1"-terphenyl-4'-carboxylate

Abstract

A simple and novel route for the synthesis of new terphenyl derivative as well as oxidative aromatization of α,β-unsaturated cyclohexenone to the corresponding phenol derivative is developed. The present work involves the condensation of ethylacetoacetate with 4,4'-difluoro chalcone followed by the aromatization using chloramine-T in acetic acid to yield the title compound (3). The synthesized compound (3) is well characterized by IR, NMR, LCMS and elemental analysis. © 2011 by the authors; licensee MDPI, Basel, Switzerland.