Half-unit dose accuracy with HumaPen® Luxura™ HD: An insulin pen for patients who need precise dosing

Abstract

Background: The HumaPen® Luxura™ HD insulin pen (Eli Lilly and Company, Indianapolis, IN) was originally designed to deliver accurate doses in half-unit increments from 1 to 30 units. Laboratory testing examined the accuracy of the initial 0.5-unit dose within a 95/95% tolerance interval with respect to a specification of ±0.5 unit (±0.005 ml). Methods: After priming, operators recorded the first 0.5 unit. Data were analyzed using k-value targets. Results: While examining 577 half-unit doses per device lot, test temperature, operator, or test liquid, at least 95% of the doses were accurate with 95% confidence. All data points were within ±0.5 unit (±0.005 ml). Conclusions: Dose accuracy of the initial half-unit is achieved with the HumaPen Luxura HD insulin pen. © Diabetes Technology Society.