α-granules are by far the most abundant platelet granules. Yet little is known about how they are formed. In this issue of Blood, Urban et al now characterize platelets from patients with an inheritable α-granule defect, demonstrating a role for VPS16B in α-granule biogenesis and taking us one step closer to understanding how these elusive organelles are formed.
CITATION STYLE
Flaumenhaft, R. (2012, December 13). αGranules: A story in the making. Blood. American Society of Hematology. https://doi.org/10.1182/blood-2012-10-459115
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