Microencapsulation of Jeringau Rhizome essential oils (Acorus calamus L.) using β-cyclodextrin

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Abstract

Background: The way to improve the stability of jeringau rhizome essential oils is microencapsulation using β-cyclodextrin. Aim: To determine the efficiency of coating the jeringau rhizome essential oil with β-cyclodextrin and examine its thermostability. Method: The microencapsulation method used was freeze-drying with a ratio of 1:20 and 1:30. Results: The microcapsule efficiency at the ratio of 1:20 and 1:30 was 81.67% and 60.70%, respectively. The thermostability test results showed that the degradation constant of 1:20 microcapsule at 50oC and ambient temperature was 0.0054 and 0.0029, respectively, with a half-life of 128.33 hours and 238.97 hours. Meanwhile, the degradation constant of 1:30 microcapsule was 0.0182 and 0.0080, with a half-life of 38.07 hours and 86.63 hours. Conclusion: The highest efficiency is in the ratio of 1:20 with a percentage of 81.67%. In the thermostability test, the 1:20 microcapsule was better protected and had a longer half-life than the 1:30 microcapsule.

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APA

Ledianasari, Tristiyanti, D., Tanjung, E. M., & Barani, L. (2021). Microencapsulation of Jeringau Rhizome essential oils (Acorus calamus L.) using β-cyclodextrin. Pharmacy Education, 21(2), 189–194. https://doi.org/10.46542/pe.2021.212.189194

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