Understanding public confidence in locally-produced mRNA vaccines: Insights for future pandemic preparedness

Abstract

As local vaccine manufacturing becomes a strategic goal for future pandemic preparedness, investigating public trust in domestic vaccine production is essential for ensuring equitable uptake and long-term success. A cross-sectional web-based survey was conducted to assess confidence in the local scientific community, manufacturers, regulatory authorities, and locally-produced mRNA vaccines. A vaccine confidence index (VCI) captured attitudes toward mRNA vaccine safety, efficacy, and acceptability. In multivariable logistic regression analysis, confidence in the competency of the local scientific community (aOR = 1.55, 95% CI: 1.14–2.10, p