Improved Epilepsy and Speech Outcomes with Human Embryonic Stem Cell Therapy in Children with Cerebral Palsy

Abstract

Title: Improved Epilepsy and Speech Outcomes with Human Embryonic Stem Cell Therapy in Children with Cerebral PalsyIntroduction:CP is a group of permanent neurological disorders which is prevalent in children of neonatal age and is often associated with epilepsy and speech disorders. The various conventional treatments and therapies available so far are unable to treat these comorbidities. In this study, we aimed to evaluate 101 patients with CP having speech disorders and epilepsy. The patients were treated using hESC therapy and assessed by Gross Motor Function Classification System - Expanded and Revised (GMFCS – E & R) score.Materials and Methods:Patients were given hESCs via different routes of administration for duration of 8 weeks and evaluated before and after the treatment on the basis of their le