The synthesis of hydrophobic 1-alkyl-1H,1′H-2,2′-bibenzo[d]imidazoles

Abstract

New synthesis of 1-alkyl-1H,1′H-2,2′- bibenzo[d]imidazoles 3 by alkylation of a disodium derivative of 1H,1′H-2,2′-bibenzo[d]imidazole 2a with alkyl halides is proposed. It is noteworthy that 1,1′-dialkylated byproducts 4 are formed in yields of <5%. The structure of all obtained compounds has been confirmed by 1H NMR, 13C NMR, and HRMS or elemental analysis.