Expression of γ/δ T cell receptors on lymphocytes from the lactating mammary gland

Abstract

γ/δ cells were at least four times more frequent in lactating mouse mammary glands than among T cells of the most proximal lymph nodes. Two-color staining of freshly isolated T cells and a study of clonally expressed γ/δ receptors on hybridomas further revealed that the mammary γ/δ population is heterogeneous, including at least three different subsets, among them cells expressing Vγ5, Vγ4 together with Vδ4, or none of these V regions. © 1990, Rockefeller University Press., All rights reserved.