Extract and Fractions from Soil Bacteria (Streptomyces canus ATCC 12647) Possess Antimicrobial and Anti-Oxidative Potential in vitro

Abstract

Streptomyces species are the most prolific producers of antibiotics within the group actinobacteria. The in-vitro antimicrobial and antioxidant activities of the methanol (MeOH) extract and vacuum liquid chromatography (VLC) fractions of a soil bacteria Streptomyces canus ATCC 12647 were evaluated. Agar well diffusion method was used for the antimicrobial assay, while phosphomolybdate and DPPH radical scavenging methods were used for the antioxidant assay. The antimicrobial assay showed remarkable activities against Bacillus subtilis, Staphylococcus aureus, and Candida albicans. Also, the extract and fractions showed good in-vitro antioxidant activities in both models. Our results showed that extract and VLC fractions from bacterial isolate had good antimicrobial and antioxidant activities.