Iron(III) chloride catalyzed glycosylation of peracylated sugars with allyl/alkynyl alcohols

Abstract

In this work, the use of ferric chloride as an efficient catalyst in glycosylation reactions of sugars in the presence of allyl and alkynyl alcohols is described. The corresponding glycosides were obtained with moderate to good yields. This new procedure presented greater selectivity when compared to classic methods found in the literature. Principal features of this simple method include non-hazardous reaction conditions, low-catalyst loading, good yields and high anomeric selectivity. © 2012 Sociedade Brasileira de Química.