Amlodipine induced gingival overgrowth-case report

Abstract

Drug induced gingival overgrowth is a well known side effect of antiepileptics, immunosuppressants and calcium channel blockers. Amlodipine is a representative of the third generation of dihydropyridine calcium antagonist that has similar pharmacodynamics effects as nifedepine but not its incidence of adverse effects in oral cavity. Amlodipine causes gingival enlargement only in a small percentage and this possibility is mostly known only onthe basis of reported case reports. By the patient, one of the main reasonsof gingival overgrowth development was the presence of periodontal disease before the calcium channel blocker therapy and high degree of gingival tissues inflammation.