Abstract
Objective: Measures of diagnostic performance in cancer are underdeveloped. Electronic clinical quality measures (eCQMs) to assess quality of cancer diagnosis could help quantify and improve diagnostic performance. Materials and Methods: We developed 2 eCQMs to assess diagnostic evaluation of red-flag clinical findings for colorectal (CRC; based on abnormal stool-based cancer screening tests or labs suggestive of iron deficiency anemia) and lung (abnormal chest imaging) cancer. The 2 eCQMs quantified rates of red-flag follow-up in CRC and lung cancer using electronic health record data repositories at 2 large healthcare systems. Each measure used clinical data to identify abnormal results, evidence of appropriate follow-up, and exclusions that signified follow-up was unnecessary. Clinicians reviewed 100 positive and 20 negative randomly selected records for each eCQM at each site to validate accuracy and categorized missed opportunities related to system, provider, or patient factors. Results: We implemented the CRC eCQM at both sites, while the lung cancer eCQM was only implemented at the VA due to lack of structured data indicating level of cancer suspicion on most chest imaging results at Geisinger. For the CRC eCQM, the rate of appropriate follow-up was 36.0% (26746/74314 patients) in the VA after removing clinical exclusions and 41.1% at Geisinger (1009/2461 patients; P
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Murphy, D. R., Zimolzak, A. J., Upadhyay, D. K., Wei, L., Jolly, P., Offner, A., … Singh, H. (2023). Developing electronic clinical quality measures to assess the cancer diagnostic process. Journal of the American Medical Informatics Association, 30(9), 1526–1531. https://doi.org/10.1093/jamia/ocad089
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