Synthesis and photophysical property studies of the 2,6,8-triaryl-4- (phenylethynyl)quinazolines

Abstract

The 2-Aryl-6,8-dibromo-4-chloroquinazolines derived from the 2-Aryl-6,8- dibromoquinazolin-4(3H)-ones were subjected to the Sonogashira cross-coupling with terminal acetylenes at room temperature to afford novel 2-Aryl-6,8-dibromo-4- (alkynyl)quinazoline derivatives. Further transformation of the 2-Aryl-6,8-dibromo-4- (phenylethynyl)quinazolines via Suzuki-Miyaura cross-coupling with arylboronic acids occurred without selectivity to afford the corresponding 2,6,8-triaryl-4- (phenylethynyl)quinazolines. The absorption and emission properties of these polysubstituted quinazolines were also determined.