Bephenium hydroxynaphthoati in treatment of ascariasis

Abstract

Different preparations of bephenium hydroxynaphthoate (“ alcopar ”) in varying doses were given to groups of children, to determine the minimum effective dose for treating ascariasis. 1.25 g. was found to be the minimum dose with optimum results. The best preparation was a freshly prepared suspension in lemon-flavoured syrup (35%). Vomiting was the only disagreeable side-effect directly attributable to the drug. It was significantly more in children under 4 years of age. The small dose recommended for treatment of ascariasis could be safely given to any age-group without causing anxiety. © 1960, British Medical Journal Publishing Group. All rights reserved.