Avaliação da atividade antibacteriana do óleo essencial de Rosmarinus officinalis L. E tintura de própolis frente à bactéria causadora da acne Propionibacterium acnes

Abstract

Acne is an extremely common skin disease. The pathogenesis of acne is multifactorial, including follicular hyperkeratinization, sebaceous hyperplasia and hypercolonization of bacteria. The Propionibacterium acnes has an important role in the inflammatory response of the pathogenesis of acne. Antibiotics are one of the drugs used in the treatment of acne. However, the adverse reactions caused by these drugs turn the treatment unpleasant, besides the existence of cases of bacterial resistance. For this reason, the use of natural products has been prominent in the dermatology area. This work intended to perform an in vitro evaluation of the possible antimicrobial effects of the essential oil of Rosmarinus officinalis and propolis tincture on the Propionibacterium acnes (ATCC 1969) strain. The essential oil was extracted by hydrodistillation, and the propolis tincture was obtained by maceration. The antimicrobial test was conducted by the tube dilution technique. The oil was tested in different concentrations varying between 16% and 0.0625%, and the tincture, between 10% and 0.072312%. We verified that the essential oil of Rosmarinus officinalis has no effects against the Propionibacterium acnes strain. The propolis tincture showed some action in several concentrations, being the minimal inhibitory concentration: 0.625%.