A Reinvestigation of the structure of zederone, a furanogermacrane-type sesquiterpene from zedoary

Abstract

The stereochemical structure of zederone, a furanogermacrane-type sesquiterpene isolated from various zedoary (Zedoariae Rhizoma), has been revised from a previously proposed structure (8a) to 8 on the basis of the NOE experiments in the IH NMR study at 500 MHz, and the absolute configuration has been determined by X-ray analysis of 12-bromozederone (9). © 1987, The Pharmaceutical Society of Japan. All rights reserved.