An HPLC-HR-MS-MS Method for identification of anticoagulant rodenticides in blood*

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Abstract

This paper presents a fully validated method for the qualitative identification of bromadiolone, brodifacoum, coumachlor, coumatetralyl, difenacoum and warfarin in whole blood specimens. Samples are protein precipitated with acetonitrile, processed via solid-phase extraction and analyzed by high-performance liquid chromatography with high resolution tandem mass spectrometric detection. Limits of detection were 10 ng/mL or better for all analytes. © Published by Oxford University Press 2013.

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Schaff, J. E., & Montgomery, M. A. (2013). An HPLC-HR-MS-MS Method for identification of anticoagulant rodenticides in blood*. Journal of Analytical Toxicology, 37(6), 321–325. https://doi.org/10.1093/jat/bkt036

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