Steroid Induced Diabetes Mellitus: An Overview

Abstract

Glucocorticoids are often used as immunosuppressant and anti-inflammatory therapy in various medical conditions. In addition to providing clinical benefits, glucocorticoids have various side effects, one of which is related to steroid-induced diabetes mellitus (SIDM). Steroid-induced diabetes mellitus can be a new onset or an exacerbation of hyperglycemia in patients who have previously been diagnosed with DM. Acute and chronic hyperglycemia due to steroids can have an impact on lengthening hospitalization, infectious complications, decreased response to therapy and increased mortality. The challenges of managing steroid-induced diabetes mellitus vary widely. Understanding of pathophysiology, risk factors, diagnosis and therapy can add insight regarding the comprehensive management of steroid-induced DM