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A Tale of two Estrogen Receptors (ERs): How Differential ER-Estrogen Responsive Element Interactions Contribute to Subtype-Specific Transcriptional Responses

  • Huang J
  • Li X
  • Qiao T
  • et al.
Nuclear Receptor Signaling (2006) 4(1)
DOI: 10.1621/nrs.04015
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Abstract

The interaction of ERα and ERβ with ERE constitutes the initial step in the canonical nuclear E2 signaling in which E2-ERβ is a weaker transactivator than E2-ERα. This perspective summarizes recent findings to discuss potential mechanisms that contribute to ER subtype-specific transcriptional responses.

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Huang, J., Li, X., Qiao, T., Bambara, R. A., Hilf, R., & Muyan, M. (2006). A Tale of two Estrogen Receptors (ERs): How Differential ER-Estrogen Responsive Element Interactions Contribute to Subtype-Specific Transcriptional Responses. Nuclear Receptor Signaling, 4(1). https://doi.org/10.1621/nrs.04015

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