Metabolic Changes Preceding Exercise-induced Bronchoconstriction

Abstract

Five asthmatics aged 25–30 were studied during bicycle ergometer and treadmill exercise. Metabolic and ventilatory changes during exercise were compared with the degree of bronchoconstriction which followed exercise. In all patients bronchoconstriction was greater after treadmill exercise. Contrary to previous suggestions, exercise-induced bronchoconstriction did not seem to be caused by lactic acidosis, increase in minute ventilation, acidaemia, hypocapnia, or change in arterial Po2. © 1972, British Medical Journal Publishing Group. All rights reserved.