Antimicrobial activity of the leaf extract and fractions of Lupinus arboreus

Abstract

The antimicrobial effect of the leaf extract and fractions of Lupinus arboreus was investigated. The\rcrude methanol extract (CME) of the dried leaves obtained by 48 h cold maceration was fractionated into\rn-hexane fraction (HEF), ethyl acetate fraction (EAF), and methanol fraction (MEF); and evaluated using\rmodified agar-well diffusion method. The results showed that the extract and fractions at varying\rconcentrations, exerted strong antimicrobial activity on some of the test organisms. However, a weak\ractivity was observed on the tested fungi-Aspergillus niger and Candida albicans. Ethyl acetate fraction\rshowed the highest activity on many organisms than extract and other fractions.\r