Identification, synthesis and structure assignment of two impurities of Erlotinib, a drug used for the treatment of some types of cancer.

Abstract

We would like to thank Conacyt for financial support (Project No. CB2015/256653). We are also grateful to SIGNA Civac S. A de C. V. for proving the starting compounds and PEI-Conacyt (Project 222400). We are grateful to María Medina from the Centro de Investigaciones Químicas UAEM, for the determination of mass spectra.