Subspecies distribution and drug-resistance characteristics of Mycobacterium abscessus complex clinical isolates in South China

Abstract

As Guangdong is a region with a high prevalence of NTM, this study investigates the epidemiological trends of MABC subspecies and their associated drug-resistance profiles, addressing a critical research gap. The findings are crucial for guiding hospital drug management and clinical decision making, enabling more accurate diagnoses and the formulation of personalized, effective treatment plans. Additionally, this study provides a valuable reference for the development of drug-resistance detection reagents and new anti-bacterial agents.