Assessment of DMFT Indexes, Salivary Flow Rate, pH, and Detections of S.Mutans Salivary Levels by a Quantitative Real-Time PCR in Polycystic Ovary Syndrome

Abstract

Objectives: PCOS is an endocrine disorder that is common in women. However, PCOS effects on oral and dental health have not been stated clearly. The aim of this study is to examine the effects of Polycystic Ovary Syndrome (PCOS), which is common in women of reproductive age, on saliva and dental tissues in these women. Materials and Methods: One-hundred individuals who were / were not diagnosed with PCOS and insulin resistance were included in this study (n=100). Subsequently, individuals, with PCOS and insulin resistance (PCOSID +), with PCOS and non-insulin resistance (PCOSID-), without PCOS and insulin resistance (ControlID +) and without PCOS and non-insulin resistance (ControlID-) were divided into 4 groups (n=25). DMFT (Decayed, Missing, Filled Teeth) index was used for dental health evaluation, while pH meter was used for saliva pH measurement. Also, Streptococcus Mutans (S. Mutans) numbers were analyzed by the real-time Polymerase Chain Reaction (PCR) method. In statistical analysis p<0.05 was considered significant. Results: In comparison among the groups, significant differences were found in terms of DMFT index, S. Mutans, and salivary pH values. Among the compared groups, the highest DMFT index, S. Mutans values were found in the PCOSID(+) group, the lowest in ControlID(-) group, while the lowest saliva pH value was found in the PCOSID(+) group. Conclusions: S. Mutans and DMFT index values were found highly in the saliva of PCOS patients, which is a multifactorial syndrome, and it is determined that salivary parameters have an effect on this situation