BODIPY-cucurbituril complexes: supramolecular approach toward improvement of photodynamic activity

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Abstract

The host-guest interaction of cucurbit[7]uril with lipophilic BODIPYs decreases their aggregation in water and improves the photophysical properties. Phototoxicity of the complex with one CB[7] moiety increased up to seven times compared to that of the free photosensitizer. This supramolecular interaction is an efficient approach to increasing the photodynamic activity of BODIPY photosensitizers.

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Demuth, J., Kaushik, R., Kozlikova, M., Rando, C., Machacek, M., Novakova, V., … Zimcik, P. (2024). BODIPY-cucurbituril complexes: supramolecular approach toward improvement of photodynamic activity. Materials Advances, 5(9), 3915–3920. https://doi.org/10.1039/d3ma01164j

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