Effects of comprehensive psychological intervention and traditional Chinese medicine on treatment adherence and quality of life in breast cancer patients undergoing chemotherapy

Abstract

This study aimed to explore how comprehensive psychological intervention combined with traditional Chinese medicine (TCM) external therapy affects treatment adherence and quality of life in breast cancer patients undergoing chemotherapy. The research included 124 patients from January 2023 to December 2023, randomly assigned to either a control group (n=60) receiving standard chemotherapy and routine care and an intervention group (n=64) receiving additional psychological support (mindfulness training, cognitive restructuring, group therapy) and TCM therapies (moxibustion, acupoint application, herbal fumigation). Results showed that the intervention group had significantly better chemotherapy completion (92.2% vs 85.0%) and dose intensity (89.1% vs 80.0%), with fewer delays (10.9% vs 20.0%) and regimen changes (15.6% vs 26.7%). Quality of life improved notably, particularly in emotional (Δ=16.7) and social functions (Δ=14.2). Psychological metrics also improved, with anxiety and depression rates dropping significantly. Additionally, the intervention group experienced fewer severe side effects such as myelosuppression, nausea, fatigue, and neuropathy. These findings suggest that combining psychological support with TCM therapies enhances treatment adherence, quality of life, and psychological well-being while reducing chemotherapy-related adverse effects, offering a promising approach for supportive care in breast cancer patients. (Afr J Reprod Health 2026; 30 [1]: 86-97).