Evaluation of anti-oxidant and antibacterial activities of Ixora chinensis and Cascabela thevetia leaf extracts: An in vitro study

Abstract

The purpose of this study was to assess the antioxidant and antibacterial activities of Ixora chinensis and Cascabela thevetia leaf. Leaf parts of Ixora chinensis and Cascabela thevetia plants were subjected to prepare the extracts with pure methanol and ethanol as solvent. These leaf extracts were evaluated for their antioxidant and antibacterial potentialities by utilizing the DPPH assay and disc diffusion methods, respectively. All the leaf extracts exhibited DPPH radical scavenging ability, among them ethanolic leaf extracts of Ixora chinensis and combined methanolic extracts of both leaf demonstrated the substantial antioxidant potentiality with the 18.52 and 29.64 µg/ml as IC50 value, respectively. In the context of antibacterial activity, both leaf extracts (Methanol and ethanol) of Cascabela thevetia showed low to moderate antibacterial activity, generating almost similar zone of inhibition against three (Staphylococcus aureus, Klebsiella pneumonia, and Vibrio cholerae C6706) of eleven investigated bacterial strains with the 7 to 10 millimeters (Diameter). The current outcomes conclude that leaf extracts of the Ixora chinensis and Cascabela thevetia could be utilized to develop the biopharmaceutical agents.